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  • Contrave is looking very promising for anyone seeking a diet plan pill that works. The U.S. Food and Drug Administration reviewed Contrave on December 7, and approved the drug 13-7, stating the advantage of the drug outweighs the potential risk of a possible surge in blood pressure. Using two separate drugs to lose weight can be very effective you can find combinations as you're watching FDA now awaiting approval. When dealing with weight reduction and the individuals who go through it one should err on the side of caution and allow the FDA do its job and demand some investigation be done so that the public knows the side effects and perils associated with the medications before we drive them. Keep in mind that drug companies have been in business to generate income and that they would say almost anything to keep people on their own medications. Researchers found that participants investing in this drug for the year, lost weight within 4 weeks and have kept the weight off through the 56 weeks in the study. Contrave is often a combination of the drugs naltrexone and bupropion, which seems to reflect a whole new trend of weight-loss drugs that are made up of multiple active ingredient, which can make them more potent and safer. Combo-pilling could be the newest fad or even better the newest into the future under scrutiny and so it is just more publicly known although in the past, comb-pilling for weight reduction has been around since the eighties. The biggest reason that employing a combination of pills is now popular will be the fact that by right now there aren't long term prescription weight loss supplements that have been authorized by the FDA besides orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications however some of the combinations happen to be rejected or have yet to be authorized by the FDA. Seizures certainly are a side effect with Contrave and really should not be taken in those with seizure disorders. The drug could also raise blood pressure level and heartrate, and really should not be used in people who have a history of cardiac arrest or stroke in the previous six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy using the drug. The FDA also warned that Contrave can raise blood pressure level and heartbeat and must not be used in patients with uncontrolled high hypertension, and also by you are not heart-related and cerebrovascular (blood vessel dysfunction impacting your brain) disease. Patients which has a history of heart attack or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes with a boxed warning to alert health care professionals and patients towards the increased risk of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for stop smoking. Acamprosate also functions eliminate the want to drink by eliminating the the cravings for alcohol consumption. The major difference between Naltrexone and Acamprosate is the fact that Acamprosate is not yet accessible in the United States. While it has been widely studied in Europe the precise chemical reason that it works is still unknown. It is belief that it disturbs receptors in the brain which process glutamate, which essentially alters just how ones body reacts to alcohol intake. Several of the European research shows a lot of promise with Acamprosate in that some of the patients had a nearly double success rate for staying sober.